Custom peptide synthesis

Giotto Biotech can syntesize peptides up to 150 AA and offers a wide range of peptide modifications.
Your project is our priority so we will start from the beginning until we get the right peptide.

WHAT INCLUDES OUR PEPTIDE SYNTHESIS SERVICE ?

Our peptide synthesis service includes the lyophilized peptide and a QC report. The QC report includes:

  • Amino acid sequence
  • Modification information
  • Peptide purity
  • Mass spectrum
  • HPLC

WHICH PURITY GRADE SHOULD I CHOOSE FOR MY PEPTIDE SYNTHESIS ?

Peptide synthesis purity grade can have an important impact on the price. However, it can also be critical for the success of your experiments. Therefore, we provide a table summarizing the peptide purity grade requested for several applications:

Peptide purity grade Applications
crude Interaction studies (ligand-receptor, protein-protein…)
Mutation screening
Sequence optimization
>70% Polyclonal antibody production
ELISA assays
>80% Monoclonal antibody production
In vitro tests
In vivo studies
Quantitative inhibition studies
Quantitative interaction studies
NMR studies
>95% Clinical trials
Crystallography
Quantitative studies


If your application is not mentioned in the table, please contact us. We will be glad to help you choose the most relevant peptide purity grade!

 

Peptide Conjugation and Modification

Giotto Biotech offers a very wide range of possible modifications. Below is a non-exhaustive list of what we offer but if you don’t find the peptide modifications you are looking for, feel free to let us know; it is very likely that we are capable of producing them.

N- C- TERMINAL MODIFICATION

3-(p-Hydroxyphenyl) propionic Acid
(Dnp, N-Terminal)
Acetylation (Lys)
Acetylation (N-Terminal)
Alloc (N-Terminal)
AMC (C-Terminal)
Amidation (C-Terminal)
Benzyloxycarbonylation (CBZ)
Br-Ac- ((N-Terminal))
CMK/FMK (C-Terminal)
DL-Lipoic acid (N-Terminal)
Fatty acid (N-Terminal)
Formylation (N-Terminal)
Lys(Pal) (middle, C-Terminal)
Maleimide (N-Terminal)
Myristic acid (N-Terminal)
NHEt (C-Terminal)
NHisopen (C-Terminal)
NHMe (C-Terminal)
OBzl (C-Terminal)
OEt (C-Terminal)
OMe (C-Terminal)
OtBu (C-terminal)
Palmitoyl (N-Terminal)
p-Nitroanilide (pNA, C-Terminal)
Succinylation (Suc, N-Terminal)
TBzl (C-Terminal)

FLUORESCENCE/DYE LABELING

(Lys(Dnp)) (middle)
(Lys(Maleimide)), (middle)
3-Indolylacetic acid (N-Terminal)
5-TAMRA (N-Terminal)
Biotin (N-Terminal, Y/N Ahx)
Biotin (Lys in sequence)
Biotin (without Lys in sequence)
Dansyl (N-Terminal, Y/N Ahx)
Dansyl (Lys in sequence)
DTPA (N-Terminal)
EDBiotin (C-Terminal)
EDDnp (C-Terminal)
FITC/5-FAM (N-Terminal, Y/N Ahx)
FITC/5-FAM (Lys in sequence)
HYNIC (N-Terminal)
Lys (Pen)
Lys(TMR) (C-Terminal)
Lys(TMR) (middle)
MCA (C-Terminal conjugated to the Lys side chain)
MCA (N-Terminal)
Palmitoylation (side chain of the Cys)
Rhodamine (N-Terminal)
Rhodamine (without Lys in sequence)
TMR (N-Terminal)

ISOTOPE LABEL

15N Ala
15N Gly
15N Val
15N Pro
15N Leu
15N Phe
15N Lys

CYCLIC PEPTIDE

Mono Disulfide bridge
Double Disulfide bridge
Triple Disulfide bridge
Amide cyclic (Side chain, end)
Intermolecular (Side chain, end)

PEPTIDE CONJUGATION

KLH / OVA / BSA-Peptide (N-Terminal or Cysteine)
Horse Radish Peroxidase (HRP)
Ovalbumin
Myoglobin

PHOSPHORYLATION

(pSer)
(pTyr)
(pThr)
Di-sites in sequence
Tri-sites in sequence

If you cannot find a modification in this list, please let us know. We can provide many other modifications, and it is difficult to gather all of them into a list.

Products are for research use only.

If you don’t see what are you looking for, please ask!
We would be happy to work with you to meet your needs.

Request a quote

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